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sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a functional deficit, and the strength and gait-speed measures that matter.

7 questions · sorted by votes

34 votes 5 answers54k views
Does an older adult need a different protein target during treatment?

I would like to know what to measure as much as what to do. I have done this once and I suspect I got away with it rather than got it right. For context: I keep…

sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

7 questions
protein-intake
protein-intake

Protein targets in grams per kilogram, per-meal distribution and the leucine threshold, and the evidence for a higher intake specifically during…

60 questions
nutrition
nutrition

Eating on a suppressed appetite: hitting nutritional targets inside a small energy budget, micronutrient risk, meal structure, and what the trial…

100 questions
asked by Dr_Ravi_Selvarajah 35k · 2.4 years ago
21 votes 2 answers7.3k views
What gait-speed change would count as clinically meaningful?

Scale weight, waist circumference and a repetition maximum, all logged weekly. I have read the primary source rather than the summary, which has left me with more…

sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

7 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
exercise
exercise

Training during substantial weight loss: cardiorespiratory work, step count, low energy availability, and how exercise interacts with the appetite…

38 questions
asked by ravenna_pace 14k · 3 months ago
21 votes 4 answers4.2k views
Is grip strength worth tracking alongside scale weight?

The trend is what I care about; individual weeks are obviously noise. I would rather over-plan the first cycle and simplify later. I am prepared to do the work if…

sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

7 questions
resistance-training
resistance-training

Loaded training as the primary intervention for retaining lean mass in a deficit: minimum effective dose, frequency versus volume, and why…

43 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
asked by pierce_count 24k · 2 months ago
14 votes 5 answers15k views
Do the trial populations say anything usable about sarcopenia risk?

The trend is what I care about; individual weeks are obviously noise. I would like to know whether this claim survives contact with evidence. If the answer is "nobody…

sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

7 questions
clinical-trials
clinical-trials

Reading the primary literature properly: estimands, intention-to-treat versus per-protocol, confidence intervals, absolute versus relative…

745 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
asked by Dr_Rosalind_Achebe 69k · 19 months ago
14 votes0 answers7.6k views
Which functional measures matter more than a DXA lean figure in older adults?

I have three DEXA scans on the same scanner at twelve-week intervals, fasted, same time of day. I want to understand what this actually establishes, as opposed to…

sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

7 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
resistance-training
resistance-training

Loaded training as the primary intervention for retaining lean mass in a deficit: minimum effective dose, frequency versus volume, and why…

43 questions
asked by h_villanueva 70k · 21 months ago
12 votes 5 answers7.9k views
How is sarcopenia distinguished from a proportional reduction in lean mass?

I would like to know what to measure as much as what to do. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to…

sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

7 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
asked by orla_sheridan 18k · 2 months ago
5 votes0 answers4.8k views
Is a sarcopenic-obesity phenotype identifiable before treatment starts?

Scale weight, waist circumference and a repetition maximum, all logged weekly. I would like help reading this properly rather than being told what conclusion to…

sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

7 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
asked by Dr_Idris_Coulibaly 33k · 15 months ago
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