Page 2 of 2 · 34 questions tagged gip-receptor.
The particulars: semaglutide · FLOW. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear that…
Numbers first: a GLP-1 receptor agonist · TRIUMPH-1. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring…
Conditions: semaglutide · STEP 5. This is one of those things that everyone repeats and nobody derives. This matters practically, not just academically, because it…
The receptor pharmacology I can follow; the in vivo translation is where I lose the thread. I would like the axes of comparison first and the recommendation second. I…
Conditions: semaglutide · ESSENCE. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review articles that come up…
The particulars: tirzepatide · SURMOUNT-5. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review articles that…
What I have: a GLP-1 receptor agonist · STEP 8. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer. I…
What I am working with: semaglutide · STEP 3. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious. My…
The case in front of me: tirzepatide · SURMOUNT-OSA. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have…
Conditions: semaglutide · SELECT. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how confident…