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dexa

Page 2 of 2 · 39 questions tagged dexa.

39 questions · sorted by votes · page 2 of 2

17 votes 5 answers13k views
What fraction of loss on oral semaglutide is lean mass according to PIONEER-4?

The case in front of me: oral semaglutide · PIONEER-4. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
oral-glp1
oral-glp1

Oral routes for GLP-1 receptor agonism: peptide formulations rescued by absorption enhancers such as SNAC, and true small molecules that need no…

219 questions
asked by Dr_Ilse_Vandenberg 113k · 19 months ago
16 votes0 answers7.2k views
What fraction of loss on semaglutide is lean mass according to ESSENCE?

The particulars: semaglutide · ESSENCE. I would like help reading this properly rather than being told what conclusion to reach. I have the full report including the…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
semaglutide
semaglutide

A GLP-1 receptor agonist with a fatty-acid-acylated backbone and a roughly one-week half-life, marketed for type 2 diabetes and for weight…

470 questions
asked by mira_sundqvist 7.1k · 11 months ago
15 votes5 answers15k views
What fraction of loss on tirzepatide is lean mass according to SURMOUNT-5?

Setup, so nobody has to ask: tirzepatide · SURMOUNT-5. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
tirzepatide
tirzepatide

A dual GIP and GLP-1 receptor agonist. Questions here cover the SURPASS and SURMOUNT programmes, the practical differences from a pure GLP-1…

370 questions
asked by gel_pack_warm 13k · 19 months ago
15 votes 5 answers12k views
What fraction of loss on semaglutide is lean mass according to FLOW?

Stated plainly: semaglutide · FLOW. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
semaglutide
semaglutide

A GLP-1 receptor agonist with a fatty-acid-acylated backbone and a roughly one-week half-life, marketed for type 2 diabetes and for weight…

470 questions
asked by teodora_ilic 17k · 7 months ago
14 votes0 answers7.6k views
Which functional measures matter more than a DXA lean figure in older adults?

I have three DEXA scans on the same scanner at twelve-week intervals, fasted, same time of day. I want to understand what this actually establishes, as opposed to…

sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

7 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
resistance-training
resistance-training

Loaded training as the primary intervention for retaining lean mass in a deficit: minimum effective dose, frequency versus volume, and why…

43 questions
asked by h_villanueva 70k · 21 months ago
12 votes 5 answers26k views
What fraction of loss on orforglipron is lean mass according to ATTAIN-1?

Details up front: orforglipron · ATTAIN-1. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
orforglipron
orforglipron

A non-peptide, orally bioavailable small-molecule GLP-1 receptor agonist studied in the ATTAIN programme. It is not a peptide, which changes…

219 questions
asked by two_point_four 8.9k · 23 months ago
12 votes5 answers12k views
What fraction of loss on semaglutide is lean mass according to STEP 8?

Numbers first: semaglutide · STEP 8. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
semaglutide
semaglutide

A GLP-1 receptor agonist with a fatty-acid-acylated backbone and a roughly one-week half-life, marketed for type 2 diabetes and for weight…

470 questions
asked by haze_check 9.3k · 9 months ago
11 votes5 answers14k views
What fraction of loss on retatrutide is lean mass according to TRIUMPH-1?

What I am working with: retatrutide · TRIUMPH-1. I have read the primary source rather than the summary, which has left me with more questions. I understand the…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
retatrutide
retatrutide

An investigational GLP-1, GIP and glucagon receptor tri-agonist, studied in the TRIUMPH programme. Not approved anywhere. Use this tag for…

251 questions
asked by shear_at_the_front 17k · 2.0 years ago
11 votes 5 answers7.8k views
What fraction of loss on semaglutide is lean mass according to STEP 3?

Numbers first: semaglutide · STEP 3. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
semaglutide
semaglutide

A GLP-1 receptor agonist with a fatty-acid-acylated backbone and a roughly one-week half-life, marketed for type 2 diabetes and for weight…

470 questions
asked by t_oyelaran 79k · 3 months ago
9 votes 3 answers8.6k views
Is a four-month stall adaptive thermogenesis or measurement error?

Intake is tracked, imperfectly, and I am aware of the direction of the error. I think I have a problem. I am not yet sure whether it is a real problem or a…

plateau
plateau

A stall in progress: distinguishing adaptive thermogenesis from measurement error from adherence drift, how long to observe before changing…

36 questions
weight-regain
weight-regain

Regain after stopping or reducing: the trajectory reported in the withdrawal extensions, how much is fluid, and what the maintenance arms tell us…

10 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
asked by lucia_marchetti 19k · 8 months ago
8 votes5 answers11k views
What fraction of loss on cagrilintide is lean mass according to REDEFINE-1?

For reference: cagrilintide · REDEFINE-1. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
amylin
amylin

Amylin and its analogues, most prominently cagrilintide, as a satiety mechanism orthogonal to incretin signalling. Includes the pharmacology of…

237 questions
asked by lukas_sedlacek 16k · 7 months ago
6 votes5 answers3.9k views
What fraction of loss on semaglutide is lean mass according to SELECT?

What I have: semaglutide · SELECT. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics change…

lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
semaglutide
semaglutide

A GLP-1 receptor agonist with a fatty-acid-acylated backbone and a roughly one-week half-life, marketed for type 2 diabetes and for weight…

470 questions
asked by Dr_Hanne_Solberg 36k · 4 months ago
5 votes0 answers4.8k views
Is a sarcopenic-obesity phenotype identifiable before treatment starts?

Scale weight, waist circumference and a repetition maximum, all logged weekly. I would like help reading this properly rather than being told what conclusion to…

sarcopenia
sarcopenia

Clinically meaningful loss of muscle mass and function, particularly in older adults on treatment. Distinguishing a proportional reduction from a…

7 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
asked by Dr_Idris_Coulibaly 33k · 15 months ago
4 votes0 answers5.1k views
Does a DEXA repeated every two weeks give me a usable lean-mass trend?

I have three DEXA scans on the same scanner at twelve-week intervals, fasted, same time of day. The comparison I want does not seem to exist anywhere in a form I can…

dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
asked by fibre_or_fragment 13k · 2.0 years ago
4 votes 5 answers4.7k views
Does a DEXA repeated every six weeks give me a usable lean-mass trend?

I would like to know what to measure as much as what to do. I would like the axes of comparison first and the recommendation second. I have tried the first option and…

dexa
dexa

Dual-energy X-ray absorptiometry: what it measures, its precision limits, why hydration state and scan positioning move the numbers, and how to…

39 questions
lean-mass
lean-mass

Lean body mass as measured rather than assumed: what DEXA, BIA and air-displacement plethysmography each actually estimate, the body-composition…

127 questions
muscle-loss
muscle-loss

Loss of contractile tissue during energy deficit: what fraction of total loss is lean mass, why the commonly quoted figures are measurement…

39 questions
asked by day_seven_trough 6.7k · 15 months ago