Page 19 of 32 · 745 questions tagged clinical-trials.
Conditions: liraglutide · tirzepatide. I am trying to choose between two options that are usually discussed as though only one exists. I am not optimising for price,…
The case in front of me: four weeks · dulaglutide. I am asking for verification rather than opinion, ideally with something I can read myself. It is possible the…
Conditions: ecnoglutide · retatrutide. I would like the axes of comparison first and the recommendation second. I have tried the first option and it works; the…
For reference: SOUL · 14 mg. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably comfortable with…
What I am working with: SURMOUNT-1 · tirzepatide. I have read the primary source rather than the summary, which has left me with more questions. I understand the…
The case in front of me: STEP 1 · semaglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the…
What I am working with: 1 mg · a GLP-1 receptor agonist. I am trying to build something sustainable rather than something thorough that I will abandon. I have already…
I have the full paper rather than the abstract, and the supplementary appendix. I am at the decision point and I would rather think it through than improvise. I would…
Setup, so nobody has to ask: tirzepatide · SURMOUNT-3. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious. My…
The case in front of me: STEP 5 · semaglutide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single…
I have been on a stable schedule for eleven weeks, so this is not a first-week question. I have the document in front of me and I can read the numbers. What I cannot…
What I have: tirzepatide · SURPASS-2. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how…
What I am working with: tirzepatide · SURMOUNT-1. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would…
Stated plainly: tirzepatide · SURMOUNT-4. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear…
Stated plainly: SURMOUNT-5 · a GLP-1 receptor agonist. I have read the primary source rather than the summary, which has left me with more questions. I understand the…
SOUL tested oral semaglutide 14 mg daily in people with type 2 diabetes and either atherosclerotic cardiovascular disease or chronic kidney disease, and reported a…
What I am working with: SURMOUNT-OSA · 10 mg. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
Numbers first: cagrilintide · 4 °C. I am asking for verification rather than opinion, ideally with something I can read myself. It is possible the evidence exists and…
Concretely: semaglutide · STEP 8. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is an…
The particulars: STEP 1 · early satiety · 1 mg. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
Concretely: 10 mg · tirzepatide. I want to decide this in advance so that I am not deciding it under pressure later. Assume I will follow the plan I write down, so I…
For reference: 15 mg · survodutide. I would like to define my thresholds before I have a result, for obvious reasons. I want a plan with explicit stopping rules, not…
I am reading the trial table rather than the press release, which is why the numbers differ. I would like the arithmetic checked rather than the conclusion asserted.…
Concretely: SELECT · nausea. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree, which is…