Page 14 of 32 · 745 questions tagged clinical-trials.
Numbers first: REDEFINE-1 · 2.4 mg. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…
The case in front of me: STEP 5 · 2 mg. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result,…
I have the full paper rather than the abstract, and the supplementary appendix. I understand the observation; what I do not understand is the mechanism behind it. I…
Stated plainly: FLOW · early satiety. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am being…
Details up front: PIONEER-1 · constipation · 7 mg. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear…
Setup, so nobody has to ask: STEP 5 · semaglutide. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
Scale weight, waist circumference and a repetition maximum, all logged weekly. I would like help reading this properly rather than being told what conclusion to…
The specifics, since they change the answer: STEP 2 · semaglutide. Somebody stated this to me confidently and I would like to check it before repeating it. I would…
What I am working with: SURMOUNT-2 · 10 mg. I would like help reading this properly rather than being told what conclusion to reach. I have the full report including…
I am asking about the protocol logic rather than about my own case specifically. I can parse the result. I am less sure what it licenses me to conclude. I have…
For reference: oral semaglutide · PIONEER-4. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried to…
I am reading the trial table rather than the press release, which is why the numbers differ. I understand the observation; what I do not understand is the mechanism…
The particulars: PIONEER-4 · oral semaglutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
Numbers first: 24 mg · orforglipron. This is a planning question. I know what my options are; I do not know how to weigh them. What I want is the minimum viable…
It has now persisted for three weeks, which is what moved this from tolerable to worth asking about. This is presented as though it settles something, and I am not…
What I am working with: FLOW · constipation. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
The specifics, since they change the answer: STEP 8 · 2 mg. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am…
The particulars: SOUL · oral semaglutide. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me at one. Is…
Setup, so nobody has to ask: orforglipron · 4 °C. This is asserted often enough that I assumed it was established, and then I went looking for the source. I have…
I have the full paper rather than the abstract, and the supplementary appendix. I would like the mechanism, because I want to be able to reason about the cases nobody…
The specifics, since they change the answer: dizziness · cagrilintide · REDEFINE-1. I have the document in front of me and I can read the numbers. What I cannot do is…
For reference: TRIUMPH-3 · nausea · 8 mg. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
I have the full paper rather than the abstract, and the supplementary appendix. I would rather understand the derivation than memorise the outcome. Two people I asked…
Conditions: STEP 4 · semaglutide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result, which…