Page 10 of 19 · 456 questions tagged titration.
Stated plainly: 1 mg · two weeks · hair thinning. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious. My…
The case in front of me: sixteen weeks · oral semaglutide. I want to know whether there is evidence behind this or only repetition. I have checked the obvious…
What I am working with: SOUL · injection-site erythema · 7 mg. I have read the primary source rather than the summary, which has left me with more questions. I…
Setup, so nobody has to ask: SOUL · reflux · 7 mg. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
For reference: 1.7 mg · three weeks · injection-site erythema. I would like the mechanism, because I want to be able to reason about the cases nobody has written…
Setup, so nobody has to ask: SURPASS-2 · 15 mg. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
The case in front of me: ATTAIN-1 · dizziness · 24 mg. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a…
For reference: 0.5 mg · three weeks · injection-site erythema. I would like the mechanism, because I want to be able to reason about the cases nobody has written…
The specifics, since they change the answer: TRIUMPH-3 · early satiety · 4 mg. I have the document in front of me and I can read the numbers. What I cannot do is…
What I have: STEP 8 · 1 mg. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s interpretation…
This came up because two published schedules for the same agent differ. I have read the primary source rather than the summary, which has left me with more questions.…
What I have: 1.7 mg · six weeks · vomiting. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer. I…
For reference: fatigue · five · a GLP-1 receptor agonist. I want a method I can write down and repeat, not a rule of thumb. I would rather over-engineer this than…
Details up front: SURMOUNT-4 · 10 mg. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
What I have: early satiety · six · dulaglutide. I am trying to do this correctly the first time rather than learn it by getting it wrong. I have already made one…
Concretely: 0.25 mg · twelve weeks · hair thinning. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the…
Conditions: SURMOUNT-1 · injection-site erythema · 15 mg. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading…
The case in front of me: vomiting · dulaglutide. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer.…
The specifics, since they change the answer: SURMOUNT-5 · headache · 5 mg. I have the document in front of me and I can read the numbers. What I cannot do is…
I have read the prescribing information and it addresses the adjacent case but not this one. I can parse the result. I am less sure what it licenses me to conclude. I…
For reference: 15 mg · ten weeks · reflux. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review articles that…
Conditions: SURPASS-3 · dizziness · 15 mg. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the…
The receptor pharmacology I can follow; the in vivo translation is where I lose the thread. Please show the division. I want to check my own against yours. I would…
The specifics, since they change the answer: SURMOUNT-1 · 5 mg. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I…